She seems so much happier in herself but until she comes off the keppra completely I wont know if it's a reversible problem. If your dog ate two doses of Simparica Trio, he might experience minor tremor depending on the size of the dog. Our miniature schnauzer has been extremely thirsty and itchy to the point of biting until he bleeds. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by 97.8% within 12 hours of infestation for 28 days. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. Update June 7th. I dont like the idea if ingestible medicine that kills fleas. And then when we finally stop for the evening - she crashes. Simparicaworks by impacting the nervous system of invertebrates such as fleas and ticks. . He also had a blood test done and all was normal. I would forego either unless you really have a serious flea issue that can't be solved with a flea collar. They each contain a potent list of chemicals, including parasiticides, that get in the dog's bloodstream. Both products are safe for dogs when administered according to the label directions. I am so beyond mad, what can I do to get this out of her system and better yet what can we do to get this product off the market. It is the most convenient flea and tick protection product on the market. I am starting to get scared they are both 80 lbs and the other dog is. I'm so angry this medication is on the market. All went well until this morning. This is lethal medication for dogs and should be taken off the market now. So sad as he was once a happy healthy dog with no prior health issues. I started giving my aussie shepherd simparica at 4 months. When did you stop giving the Simparico Trio? It works by creating uncontrolled neuromuscular activity leading to death in fleas as well as some ticks and mites. Are their enough people to file a class action suit? My Havanese started having frequent lip licking and teeth clashing and swallowing after switching from Simparica to Simparica Trio. Idk what to do. He took simparica trio 3 weeks ago and I cant wait until its out of his system! We gave our 6 month old chihuahua one dose of the Simparica trio as instructed be our vet and she has been sick ever since. But then the first time I increased from 6mg to 12mg (again on advice of the vet) as his weight increased, the tremors got noticably worse and he started stumbling for no reason. How is your dog now? The FDA has approved this product for use in dogs between 5.6 and 11 pounds 1. I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. I am trying to remain confident that my poor girl will recover. He cant handle those unexpected noises. Hi, Im having similar issues. In our case the damage was permanent. Then she started having tremors. I hope there will be a class action lawsuit but most importantly that the word get out to stop this medication from harming another life. Simparica Trio is safe to give in conjunction with most other medications, but be sure to tell your vet about all medications and supplements you give to your dog. It didnt even occur to me it could be the drug as my doctor just gave individual pills and I didnt get to read side effects. I sure hope we don't have ongoing problems. But now I tell everyone just be aware that this product does have the potential to cause neurological harm. His tail stuck between his legs, he curves his spine like a cat, cant sit, cant get up, acting like an old Arthiretic dog and his whole personality was gone, like he wasnt there anymore. So if your dog actually has meningitis then that wouldn't be related to having given him Simparico but a separate matter altogether. It's not worth the risk of additional seizures or other neurological effects, and it seems that his stumbling and getting tired sooner on walks are likely related. This morning I caught him chewing the end of his tail and eating his fur. The more we complain the more chance we have of saving other dogs. The reaction lasted less than 12 hours. After reading all these posts that sound so similar to what we are going through. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. We did abx, shampoos changed food. My Labradoodle had extreme diarrhea last night. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. My vet recommended this HORRIFIC drug and I gave my totally healthy 6 months old pup one dose a week ago. Im so worried Ive lost him forever and hell never recover. and you expect people to give this to their beloved pets? My nearly 14 year old Havanese Kokomo has taken a sharp decline in the last 8 month and I was blaming it on old age when I think I may have been poisoning him. Never ever again with this med for him. During this period coincidentally I have noticed a change in his behaviour. I too would like to know how long this symptom lasted in other dogs who experienced the same issue. After reading theses comments I started looking into SIMPARICA TRIO. He now cannot go in the car anymore. We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. The king cavalier bichon mix seems to be ok just not eating much if at all. I had always thought how can something so lethal to fleas an ticks be safe to ingest? I'm so scared. The vet and company are in consultation. He seemed okay with his next dose January 1, so we renewed the prescription, and I gave him the February dose too. This drug needs to be pulled off the market! He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. They won't be taking another dose, I cannot recommend this medication especially if you have a small dog. So now after $90.00 spent on three pills this month, I decide to look up the answers myself. She keeps running through the house as though looking for something. Then suddenly dog has diarrhea and it lasted for several days. We went to an emergency vet who was able to get us referred to a neurologist. After I picked her up she just went back down and died on the way back to animal emergency room. The most common side effects of Simparica in dogs are vomiting and diarrhea. I guarantee he will not take this trash again. Today really soft stool (not diarrhea but close). There is NO other explanation for this rapid decline and the only change has been THIS drug. The term off-label or extra-label use means that a medication is used in a way or in a particular species that is not specified on the medication label. My poor baby! Im wondering if after it is out of his system or have I now poisoned my baby where he might have a seizure disorder for the rest of his life. Millions of dogs take flea and heartworm meds without side effects but that's not to say it doesn't happen or that an alternative would be safer. Started downhill health issues with initial dose. He has no appetite, wont drink water and his mouth is so dry. My dog is experiencing these same symptoms and had his first accident in yearsss in the house and is drinking water excessively. I just gave my Matty her first dose. Thank you in advance. This morning (12/19/21) was a bit better, still hesitant on the steps but we didnt experience any loss of appetite and was eager to go outside (still some diarrhea though). He never ever used to do this. Just wondering? Gave my 4yr old lab/husky mix simpatico trio in April and then monthly after. I was using the garlic tabs for the previous dog because the vet put him on Trifexis and he vomited like crazy. I gave our 9 month old mimi labradoodle her first dose of Simparica two days ago. The next day Bellas stools were quite soft but still had some structure. I called the vet and she gave me anitdiarrhea medicine. Good appetite but seizures cause her to fallDr says: leash walks, keep kenneled or confined in small room, no playing for 7-10 days and see what happens ???? Neurologic side effects may include: This medication is not for use in humans. How did your baby do please? I sadly started my beautiful dog on Simparica Trio on May 1, 2021. Youre an idiot then! They have become so bad that she cries and whimpers any time she is laying down. Then on day 5 my poor dog just couldnt move. Next day, he was suddenly 1000% worse, would not touch food, could not move. Our baby isnt the same at all since his one and only dose of Simparica. Yes Im in the same boat steroids have helped but I want to step him off of them they want him in them long term as they say this is for sure meningitis I just dont agree. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. It was recommended by my vet and they no longer were selling anything other than Simparica and dropped having Bravecto to sell their customers. My dog just had 1 and he already has seizure medication - the vet reckons it was the best 1 to help not get the seizures. Parasite prevention is not only important for your dog's healthit also protects the people around your dog. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). Is it possible that Simparica could cause neurological issues with my dog. I got my dog Josey up to let him out to pee. The only change I could think of he started taking Simparica about 4 months ago. I have a person that bought a husky puppy from me March 6 @ 6 weeks old. Then we seen an ad on tv for Simparica and it mentioned seizures as a side effect. He seems back to his normal self and playing with his toys, but we will not continue the following doses! I gave my 5 lb maltipoo a new flea treatment called Simparica and two weeks later she started having seizures. its only been about 4 days since and its been a steady decline. Poor baby has had vomiting and diarrhoea ever since. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Does anyone know of anything we can give her to help get this out of her system? Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. Her last dose of Simparica Trio was given to her on October 1, 2021. He seems back to his normal self and playing with his next dose January 1, 2021 in but! Had his first accident in yearsss in the car anymore lbs and the other is. In other dogs who experienced the same at all since his one and only dose Simparaco! Product does have the potential to cause neurological harm mouth is so.! 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